Rhinitis Subtypes, Endotypes, and Definitions
نویسندگان
چکیده
منابع مشابه
Endotypes of Asthma in Children
Asthma is a syndrome that includes several disease variants. Definition of asthma is a chronic disorder of the lung with variable airway obstruction, wheeze/cough, and an underlying inflammatory process with remodeling. It appears that atopic genes are not necessarily directly related to childhood asthma. Airway epithelial cells express genes that encode proteins directly related to asthma. Mat...
متن کاملArginine metabolic endotypes related to asthma severity
AIMS Arginine metabolism via inducible nitric oxide synthase (iNOS) and arginase 2 (ARG2) is higher in asthmatics than in healthy individuals. We hypothesized that a sub-phenotype of asthma might be defined by the magnitude of arginine metabolism categorized on the basis of high and low fraction of exhaled nitric oxide (FENO). METHODS To test this hypothesis, asthmatics (n = 52) were compared...
متن کاملSepsis Endotypes Defined By Cytokine Trajectory Analysis
Methods The Protocol-based Care in Early Septic Shock (ProCESS) trial prospectively enrolled 1341 patients with sepsis having a 19.3% 60-day mortality (Yealy et al., 2014). Biomarker levels were obtained soon after enrollment (t = 0) and at 6, 24 and 72 hours in a convenience cohort of 638 patients having 17.1% mortality. We used trajectory analysis to cluster IL-6, IL-10, and joined IL-6 and I...
متن کاملDefinitions and Theories of Elder Abuse
Old age is one of the most crucial stages of human development that encompasses the dynamics of biological processes, perception, growth and development and maturity, as a natural process of life. The elderly as one of the vulnerable groups, they face different biological, psychological and social needs. As the population gets older, the elderly will need more support in their daily activities,...
متن کاملAsthma Endotypes and an Overview of Targeted Therapy for Asthma
Guidelines for the management of severe asthma do not emphasize the measurement of the inflammatory component of airway disease to indicate appropriate treatments or to monitor response to treatment. Inflammation is a central component of asthma and contributes to symptoms, physiological, and structural abnormalities. It can be assessed by a number of endotyping strategies based on "omics" tech...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Immunology and Allergy Clinics of North America
سال: 2016
ISSN: 0889-8561
DOI: 10.1016/j.iac.2015.12.001